Coravid ofloxacin tablets

CORAVID is a quinolone antimicrobial agent. The mechanism of action is by inhibition of bacterial topoisomerase IV and DNA gyrase enzymes required for bacterial DNA replication, transcription, repair and recombination.
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Description

Composition; Each film-coated tablet contains ……….Ofloxacin USP 200/400mg 
Pharmacological Category. An antimicrobial agent
 
Mechanism of action: CORAVID is a quinolone antimicrobial agent. The mechanism of action is by inhibition of bacterial topoisomerase IV and DNA gyrase enzymes required for bacterial DNA replication, transcription, repair and recombination. 
 
Indications: Ofloxacin is an antibiotic that belongs to the class of medications called quinolones. It is used to treat certain infections caused by bacteria. It is most commonly used to treat infections of the lung, urinary tract, and skin. It can also be used to treat certain prostate infections and sexually transmitted infections. Ofloxacin works by killing some types of bacteria that can cause these infections. Ofloxacin is used to treat pneumonia and bronchitis caused by Haemophilus influenzae and Streptococcus pneumoniae
It also is used in treating skin infections caused by Staphylococcus aureus and Streptococcus pyogenes bacteria. Ofloxacin is used to treat sexually transmitted diseases, such as gonorrhoea and chlamydia, but is not effective against syphilisOfloxacin is used often to treat urinary infections and prostate infections caused by E. Coli. Some strains of Streptococcus, Enterococcus and anaerobic bacteria are resistant to ofloxacin. 
 
DOSING: The usual dose for patients with normal renal function is 200 to 400 mg every 12 hours. Dosages require adjustment in patients with severely abnormal liver or kidney function. 
 
SIDE EFFECTS: The most frequent side effects of ofloxacin include nauseavomitingdiarrheainsomnia, headachedizzinessitching, and vaginitis in women. 
 
SIDE EFFECTS: The most frequent side effects of ofloxacin include nauseavomitingdiarrheainsomnia
headachedizzinessitching, and vaginitis in women. 
 
PREGNANCY: Ofloxacin should be avoided during pregnancy because it is secreted in breast milk and can cause adverse events in the infant. NURSING MOTHERS: Ofloxacin should be avoided in nursing mothers, as safe use has not been established.  
DRUG INTERACTIONS: Ofloxacin reduces the elimination of theophylline, elevating blood levels of theophylline.
If concurrent use of ofloxacin and theophylline cannot be avoided, frequent blood tests to monitor theophylline blood levels should be performed. Ofloxacin can enhance the action of the anticoagulant warfarin, and increase the risk of bleeding. Both high and low blood sugar levels have been reported, especially in patients with diabetes who were also receiving insulin or other medications used to lower the blood sugar. Careful monitoring of blood sugar levels is recommended. Sucralfate, iron, multivitamins containing zinc, didanosine, as well as antacids containing calcium, magnesium, or aluminium should not be taken within two hours before or after taking ofloxacin. 
 
WARNING: This medication may rarely cause tendon damage (such as tendonitis, tendon rupture) during or after treatment. Your risk for tendon problems is greater if you are over 60 years of age, if you are taking corticosteroids (such as prednisone), or if you have a kidney, heart, or lung transplant. Stop exercising, rest, and get medical help right away if you develop joint/muscle/tendon pain or swelling.  
Ofloxacin should not be used by patients with myasthenia gravis. It may cause the condition to become worse. Get medical help right away if you develop muscle weakness or trouble breathing. 
Identification: Coravid 400mg comes in a white coloured, oblong, film-coated tablet having break line on 
one side presented as 1×10 Alu-Alu blister in a blue carton. 
Coravid 200mg comes as a white coloured biconvex, film-coated tablet in 1×10 Alu-Alu blister. For detailed product information, please read the leaflet insert. CORAVID is a prescription-only medicine (POM).
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